---

プレドニゾロン長期投与中に化膿性肺炎で死亡した
バンドウイルカ（Tursiops truncatus）1例
寺沢 文男(1) ・ 櫻木 徹(1) ・ 野村 綾(1) ・ 高橋 公正(2)
　(1) 新江ノ島水族館
　(2) 日本獣医生命科学大獣医病理学教室

要 約
第1病日、推定19歳以上の雌のバンドウイルカが肛門に黒色粘性便を付け食欲廃絶した。第8病日プレドニゾロンは120mg（0.45mg/kg）から始め、抗生物質を併用し23ヵ月投与した。状態を見て減量し第72病日より49日休薬できた。第151病日より再発した。減量を試みたが、状態悪化を繰り返し、死亡するまでプレドニゾロンは0.09～0.92mg/kgで投与し続けた。第726病日、化膿性肺炎で死亡した。



Fetal Purulent Pneumonia in a Bottlenose Dolphin （Tursiops truncatus）
with Long-Term Prednisolone Administration
Fumio TERASAWA(1), Toru SAKURAGI(1), Aya NOMURA(1) and
Kimimasa TAKAHASHI(2)
　(1) Enoshima Aquarium
　(2) Department of Veterinary Pathology,
　　　Nippon Veterinary and Animal Science University

ABSTRACT
On day 1, a female bottlenose dolphin (Tursiops truncatus) estimated to be more than 19-years-old, became anorexic and had viscous black feces adhered to its anus. On day 8, prednisolone 120mg (0.45mg/kg) began to be administered. Thereafter, the dolphin was treated in combination with prednisolone and antibiotics over approximately 23 months. Prednisolone was tapered based on the clinical condition, and withdrawn for 49 days from day 72. However, on day 151, the symptoms returned and prednisolone therapy was restarted. Prednisolone therapy, the doses of 0.09-0.92 mg/kg, should have to be continued until its death because whenever the symptoms were relapsed in the course of tapering prednisolone. On day 726, the dolphin died of purulent pneumonia.